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- [Instructor] Most of us have heard of double-blind studies

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but most data scientists don't work in a setting,

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or an industry where they get an opportunity to conduct them

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A more complete name is a randomized

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double-blind placebo control study.

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They are often described with phrases

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like "the best method," or "the gold standard,"

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or "least likely to be biased,"

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or "the most convincing."

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That can inspire feelings of frustration

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because many of us are competing with the reputation

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of a technique that is not available to us.

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We'll discuss alternatives in this course,

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so we will have options but let's first,

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get clear about what the features are,

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and why they are considered so attractive.

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What makes it a double-blind?

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In a double blind-study, not only the patient

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but also the clinician is unaware of the assignment.

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The assignment being whether or not

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the patient was given the treatment, or the placebo.

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Without blinding the patient's beliefs

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in the efficacy could impact the results.

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The purpose of double blinding is that the clinician

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could accidentally give subtle clues during the treatment.

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There's even something called triple blinding

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where even the data analysts, and researchers

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don't know which group is which.

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So let's recap with a list of these characteristics.

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There's a placebo group, there's randomization,

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it's prospective meaning that assignment to treatment,

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or a placebo is done before the study begins.

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And finally, as we've discussed, there is blinding.

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These characteristics work together

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to produce the type of study that most scientists,

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and statisticians find the most convincing.


