Yoshinori Osumi was born in Fukuoka
Japan in 1945 he started the seminal
work for which he is awarded a Nobel
Prize at York University this yields
Nobel Prize in Physiology or medicine is
awarded for discoveries concerning out
of regime the word out of Beijing is
derived from the Greek language and
means self eating to eat oneself in the
human body self eating out of a gene is
a process by which ourselves reduce
their own components to release energy
and to build new functional parts
Yoshinori assuming decided the product
to study the process of al-tofah G in
baker's yeast yeast cells contain a
single large lysosome known as the
vacuole Osumi found a clever way to
visualize the accumulation of
out-of-focus ohm's in the vacuole by
making star cells unable to degrade the
content of the vacuum he then use this
method to search among thousands of
mutants for yeast cells that had lost
the capacity to activate out of a G this
ingenious strategy led to the discovery
that our tofu G is regulated by a large
number of genes as many as 15 essential
out of G genes were identified in the
first study published in 1993 having
discovered the El Topo Gigio Sumi moved
on to the next question that was to
understand how the products of the genes
work together
thanks to this pioneering work we have
today a detailed understanding of the
molecular mechanism of ecology we now
know that Altaf AG regulates important
physiological at the cells
and that defects of auto Fuji are
associated with many human diseases
through the removal of damaged proteins
and organelles out of a jeep remote cell
renewal failure of Vltava G is therefore
associated with cell aging and with many
diseases of old age
Sanchez Alzheimer disease and type 2
diabetes finally too much of tofu G may
have undesired effects in Kansas for
example in cancer where El Topo chicken
promotes the growth of tumor cells and
the resistance to anti-cancer drugs the
discoveries made I by your scenario
Suman have been instrumental in
revealing the mechanism and significance
of a fundamental physiological process
and there is growing hope that this
knowledge will lead the development of
new strategies for the treatment of many
human diseases